abstract：:The effects of osmolytes on the unfolding and refolding process of recombinant human brain-type creatine kinase (rHBCK) were comparatively, quantitatively studied in dilute solutions and macromolecular crowding systems (simulated by 100 g/L polyethylene glycol 2000), respectively. The results showed that the osmolytes...

journal_title：International journal of biological macromolecules

authors： Fan YQ,Lee J,Oh S,Liu HJ,Li C,Luan YS,Yang JM,Zhou HM,Lü ZR,Wang YL

更新日期：2012-12-01 00:00:00

abstract：:Chitin/alginate (CA) blend membranes were successfully prepared from 8 wt% NaOH/4 wt% urea aqueous solution by coagulating with 0.5M CaCl(2) aqueous solution containing 5 wt% HCl. Morphology, mechanical properties, thermal stability, and antimicrobial effects of the membranes were investigated by scanning electron mic...

journal_title：International journal of biological macromolecules

authors： Li G,Li W,Deng H,Du Y

更新日期：2012-12-01 00:00:00

abstract：:In recent years, aging has been reported to be regulated by HAT. In this study, the inhibitory effects of spermidine on the matrix metalloproteinase-2 (MMP-2) activity and expression were investigated in human dermal fibroblasts (HDFs). It was observed that spermidine inhibits MMP-2 activity and expression. In additio...

journal_title：International journal of biological macromolecules

authors： Park IH,Kim MM

更新日期：2012-12-01 00:00:00

abstract：:Limonium sinense (Girard) Kuntze is a traditional Chinese folk medicine used for the treatment of fever, hemorrhage, hepatitis and other disorders. The study focused on the antitumor and immunomodulatory activities of L. sinense polysaccharides (LSP) which was obtained from the root of the plant. The antitumor effects...

journal_title：International journal of biological macromolecules

authors： Tang XH,Yan LF,Gao J,Yang XL,Xu YX,Ge HY,Yang HD

更新日期：2012-12-01 00:00:00

abstract：:Three fractions of the endo-polysaccharides from the mycelium of Hericium erinaceus (HEP) grown on tofu whey were obtained by the fractional precipitation with gradient concentrations of ethanol (HEP40, HEP60 and HEP80). The chemical and physical characteristics of the three crude polysaccharides were investigated by ...

journal_title：International journal of biological macromolecules

authors： Zhang Z,Lv G,Pan H,Pandey A,He W,Fan L

更新日期：2012-12-01 00:00:00

abstract：:The biosynthesis of medium chain length poly(3-hydroxyalkanoates) mcl PHAs by Pseudomonas guezennei using glucose, sodium octanoate, and 10-undecenoic acid as sole or mixed carbon sources was investigated. Chemical composition of polyesters was analyzed by GCMS and NMR. The copolyester produced by P. guezennei from gl...

journal_title：International journal of biological macromolecules

authors： Simon-Colin C,Gouin C,Lemechko P,Schmitt S,Senant A,Kervarec N,Guezennec J

更新日期：2012-12-01 00:00:00

abstract：:The purpose of this study was to develop a new therapeutic approach for atorvastatin (ATV) adopting nanostructured polymeric micelles for its controlled delivery to the cancer cells. Amphiphilic block copolymers of stearyl chitosan (SC) and sulfated stearyl chitosan (S-SC) that could self assemble to form polymeric mi...

journal_title：International journal of biological macromolecules

authors： Mekhail GM,Kamel AO,Awad GA,Mortada ND

更新日期：2012-11-01 00:00:00

abstract：:Carboxymethyl potato starch (CMPS) was synthesized with a simple dry and multi-step method as a product of the reaction of native potato starch and monochloroacetic acid in the presence of sodium hydroxide. The influence of the molar ratio of sodium hydroxide to anhydroglucose unit, the volume of 95% (v/v) ethanol, th...

journal_title：International journal of biological macromolecules

authors： Zhang B,Gong H,Lü S,Ni B,Liu M,Gao C,Huang Y,Han F

更新日期：2012-11-01 00:00:00

abstract：:In this paper, the composition and biological activities of polysaccharides from Inula britannica flower IBP obtained by water extraction were investigated. The properties and chemical compositions of IBP were analyzed with HPLC and IR methods. The results showed that IBP consisted of two kinds of polysaccharides with...

journal_title：International journal of biological macromolecules

authors： Hong T,Zhao J,Dong M,Meng Y,Mu J,Yang Z

更新日期：2012-11-01 00:00:00

abstract：:A comparison of cross-linked and native gliadin suspensions, with respect to the state of protein globular structure was carried out using small-angle X-ray scattering (SAXS), dynamic light scattering (DLS) and rheological analysis. Gliadin suspensions were also analyzed in the presence and absence of glycerol. DLS an...

journal_title：International journal of biological macromolecules

authors： Soares RM,Lionzo MI,Da Silveira NP,Rayas-Duarte P,Soldi V

更新日期：2012-11-01 00:00:00

abstract：:Biopolymer used for the production of nanoparticles (NPs) has attracted increasing attention. In the presence article we use aqueous solution of polysaccharide Cyamopsis tetragonaloba commonly known as guar gum (GG), from plants. GG acts as reductive preparation of silver nanoparticles which are found to be <10 nm in ...

journal_title：International journal of biological macromolecules

authors： Pandey S,Goswami GK,Nanda KK

更新日期：2012-11-01 00:00:00

abstract：:Ionic liquids have shown their potential as a solvent media for many enzymatic reactions as well as protein preservation, because of their unusual characteristics. It is also observed that change in cation or anion alters the physiochemical properties of the ionic liquids, which in turn influence the enzymatic reactio...

journal_title：International journal of biological macromolecules

authors： Naushad M,Alothman ZA,Khan AB,Ali M

更新日期：2012-11-01 00:00:00

abstract：:The extracellular fructosyltransferase (FTase) of a novel strain of Bacillus licheniformis capable of producing fructooligosaccharides (FOS) and a polysaccharide type levan was obtained and partially purified. The purification was achieved by ammonium sulfate precipitation, DEAE cellulose and gel filtration chromatogr...

journal_title：International journal of biological macromolecules

authors： Dahech I,Belghith KS,Belghith H,Mejdoub H

更新日期：2012-10-01 00:00:00

abstract：:A simple and valid ultraviolet (UV) spectrophotometric method for the determination of poly(γ-glutamic acid) is developed. The method is based on the UV absorption spectrum of γ-PGA in aqueous solution, which exhibits a maximum absorption wavelength at 216 nm. The results obtained were comparable to those obtained wit...

journal_title：International journal of biological macromolecules

authors： Zeng W,Chen G,Zhang Y,Wu K,Liang Z

更新日期：2012-07-01 00:00:00

abstract：:We report the synthesis of a series of ionic liquids (ILs) from various ions having different kosmotropicity including dihydrogen phosphate (H(2)PO(4)(-)), hydrogen sulfate (HSO(4)(-)) and acetate (CH(3)COO(-)) as anions and chaotropic cation such as trialkylammonium cation. To characterize the biomolecular interactio...

journal_title：International journal of biological macromolecules

authors： Attri P,Venkatesu P

更新日期：2012-07-01 00:00:00

abstract：:Copper is known to exert diverse effects on the self-association of proteins and has been found in amyloid deposits that are involved in neurodegenerative disease processes. The effects of the metal ion on the protein during fibrillation were investigated by fluorescence, circular dichroism spectroscopy and fluorescen...

journal_title：International journal of biological macromolecules

authors： Ghosh S,Pandey NK,Bhattacharya S,Roy A,Dasgupta S

更新日期：2012-07-01 00:00:00

abstract：:In the present study, the formation of one molten globule-like unfolding intermediate of bovine serum albumin (BSA) at pH 11.2 has been established with the help of circular dichroism (CD) spectra, fluorescence spectroscopy and 'phase diagram' approach. Additionally, we have shown the conformational changes occurring ...

journal_title：International journal of biological macromolecules

authors： Qu P,Wang Y,Wu G,Lu Z,Xu M

更新日期：2012-07-01 00:00:00

abstract：:Until now, there is a lack of knowledge about the presence of chitin in numerous representatives of corals (Cnidaria). However, investigations concerning the chitin-based skeletal organization in different coral taxa are significant from biochemical, structural, developmental, ecological and evolutionary points of vie...

journal_title：International journal of biological macromolecules

authors： Bo M,Bavestrello G,Kurek D,Paasch S,Brunner E,Born R,Galli R,Stelling AL,Sivkov VN,Petrova OV,Vyalikh D,Kummer K,Molodtsov SL,Nowak D,Nowak J,Ehrlich H

更新日期：2012-07-01 00:00:00

abstract：:In this article, modified κ-carrageenan hydrogel nanocomposites were synthesized to increase the release ability of carrageenan hydrogels under gastrointestinal conditions. The effect of MgO nanoparticle loading in a model drug (methylene blue) release is investigated. Characterization of hydrogels were carried out us...

journal_title：International journal of biological macromolecules

authors： Hezaveh H,Muhamad II

更新日期：2012-06-01 00:00:00

abstract：:The aim of this study was to investigate the role of process conditions and system composition on the acid-induced gelation of a mixture of milk protein and gum tragacanth. This was studied by determining the effects of co-solute (lactose) addition (3, 5 and 7%) and gelation temperature (25, 37 and 45°C) on the mixtur...

journal_title：International journal of biological macromolecules

authors： Hatami M,Nejatian M,Mohammadifar MA

更新日期：2012-05-01 00:00:00

abstract：:Lactoglobulin is a globular milk protein for which physiological function has not been clarified. Due to its binding properties lactoglobulin might serve as a carrier for bioactive molecules. Binding of 12-, 14-, 16- and 18-carbon saturated fatty acids to bovine β-lactoglobulin has been characterised by isothermal tit...

journal_title：International journal of biological macromolecules

authors： Loch JI,Polit A,Bonarek P,Olszewska D,Kurpiewska K,Dziedzicka-Wasylewska M,Lewiński K

更新日期：2012-05-01 00:00:00

abstract：:Thermo-sensitive poly(N-isopropyl acrylamide-co-vinyl pyrrolidone)/chitosan [P(NIPAM-co-NVP)/CS] semi-IPN hydrogels with improved loading capacity and sustained release for anionic drugs NAP were prepared by free-radical polymerization. The LCST of hydrogels was adjusted to the vicinity of body temperature by introduc...

journal_title：International journal of biological macromolecules

authors： Li G,Guo L,Chang X,Yang M

更新日期：2012-05-01 00:00:00

abstract：:The thermal stability and enzymatic activity of bovine pancreatic ribonuclease A (RNase A) have been investigated in the presence of a homologous series of cationic gemini surfactants (alkanediyl-α,ω-bis(hydroxyethyl methyl hexadecyl ammonium bromide)). UV, circular dichorism and fluorescence spectroscopies have been ...

journal_title：International journal of biological macromolecules

authors： Amiri R,Bordbar AK,Laurents DV,Khosropour AR,Mohammadpoor-Baltork I

更新日期：2012-05-01 00:00:00

abstract：:Photo catalytic action of nano TiO(2) for decomposing of some organic compounds is a well known phenomenon. This can be extended to the application on nano TiO(2) on the desized cotton fabric to decompose the hydrophobic impurities and coloring matters of the fabric. This can be nominating as a replacement for the con...

journal_title：International journal of biological macromolecules

authors： Montazer M,Morshedi S

更新日期：2012-05-01 00:00:00

abstract：:Effect of Zn(2+) ions on DNA transition from B-form to a metallized form (m-DNA) in Tris and tetraborate buffers at pH 8.5 has been studied by visible and differential UV-spectroscopy and by thermal denaturation. The results have been compared to those obtained at pH 6.5 in cacodylate buffer. It was found that in alka...

journal_title：International journal of biological macromolecules

authors： Sorokin VA,Valeev VA,Usenko EL,Andrushchenko VV

更新日期：2012-04-01 00:00:00

abstract：:Three polysaccharide fractions (TPS1, TPS2 and TPS3) with different molecular weights were obtained using ultra filtration membranes from crude tea polysaccharide (CTPS) extracted from abandoned lower grade tea leaves. Each fraction contained different contents of neutral sugar, uronic acid, protein, and total polyphe...

journal_title：International journal of biological macromolecules

authors： Wang Y,Yang Z,Wei X

更新日期：2012-04-01 00:00:00

abstract：:This study is to synthesize sulfated Angelica polysaccharides (APSs) and investigate the activity of one of the sulfated derivatives APS-1 on murine leukemia virus in vivo. Six sulfated derivatives with degree of sulfation ranging from 0.68 to 1.91 were obtained. And the virus replication was inhibited by APS-1 at the...

journal_title：International journal of biological macromolecules

authors： Yang T,Jia M,Zhou S,Pan F,Mei Q

更新日期：2012-04-01 00:00:00

abstract：:To contribute towards effective exploitation and utilization of spent mushroom substrate (SMS), a water-soluble polysaccharide named PL was isolated and purified from SMS. The total sugar content and monosaccharide composition were analyzed by phenol-sulfuric acid method and capillary electrophoresis, and infrared spe...

journal_title：International journal of biological macromolecules

authors： Zhu H,Sheng K,Yan E,Qiao J,Lv F

更新日期：2012-04-01 00:00:00

abstract：:An unidentified Bacillus licheniformis trehalose-6-phosphate hydrolase (BlTreA) gene was cloned and heterologously expressed in Escherichia coli M15 cells. The over-expressed BlTreA was purified to apparent homogeneity by metal-affinity chromatography and its molecular mass was determined to be approximately 65.9 kDa....

journal_title：International journal of biological macromolecules

authors： Chuang TT,Ong PL,Wang TF,Huang HB,Chi MC,Lin LL

更新日期：2012-04-01 00:00:00

abstract：:Cationic starch nanoparticles were obtained by aqueous polyelectrolyte complex formation between cationic quaternary ammonium substituted starches and anionic sodium tripolyphosphate. The formation of nanosized starch particles of spherical shape was verified by dynamic light scattering and scanning electron microscop...

journal_title：International journal of biological macromolecules

authors： Rutkaite R,Bendoraitiene J,Klimaviciute R,Zemaitaitis A

更新日期：2012-04-01 00:00:00

abstract：:In this study, the water-soluble selenium-enriched exopolysaccharides (Se-ECZ-EPS) were isolated from submerged culture broth of Enterobacter cloacae Z0206 through fermentation, ethanol precipitation and deproteinization. The protective effects of Se-ECZ-EPS on alloxan-induced diabetic mice were investigated. Diabetes...

journal_title：International journal of biological macromolecules

authors： Jin M,Lu Z,Huang M,Wang Y,Wang Y

更新日期：2012-03-01 00:00:00

abstract：:Interpenetrating polymer network (IPN) hydrogel microspheres of sodium carboxymethyl cellulose (NaCMC) and poly(vinyl alcohol) (PVA) were prepared by water-in-oil (w/o) emulsion crosslinking method for oral controlled release delivery of a non-steroidal anti-inflammatory drug, diclofenac sodium (DS). The microspheres ...

journal_title：International journal of biological macromolecules

authors： Banerjee S,Siddiqui L,Bhattacharya SS,Kaity S,Ghosh A,Chattopadhyay P,Pandey A,Singh L

更新日期：2012-01-01 00:00:00

abstract：:Five water-soluble chitosan derivatives were carried out by quaternizing either iodomethane or N-(3-chloro-2-hydroxypropyl) trimethylammonium chloride (Quat188) as a quaternizing agent under basic condition. The degree of quaternization (DQ) ranged between 28±2% and 90±2%. The antifungal activity was evaluated by usin...

journal_title：International journal of biological macromolecules

authors： Sajomsang W,Gonil P,Saesoo S,Ovatlarnporn C

更新日期：2012-01-01 00:00:00

abstract：:A chitosan-glutaraldehyde crosslinked uricase was immobilized onto Prussian blue nanoparticles (PBNPs) absorbed onto carboxylated multiwalled carbon nanotube (c-MWCNT) and polyaniline (PANI) layer, electrochemically deposited on the surface of Au electrode. The nanohybrid-uricase electrode was characterized by scannin...

journal_title：International journal of biological macromolecules

authors： Rawal R,Chawla S,Chauhan N,Dahiya T,Pundir CS

更新日期：2012-01-01 00:00:00

abstract：:Novel carboxymethyl guar gum (CMG)-chemically modified multiwalled carbon nanotube (MCNT) hybrid hydrogels were synthesized at different MCNT levels as potential device for sustained trans-dermal release of diclofenac sodium. Spectroscopy together with morphology, thermogravimetry, and rheological studies proved relat...

journal_title：International journal of biological macromolecules

authors： Giri A,Bhowmick M,Pal S,Bandyopadhyay A

更新日期：2011-12-01 00:00:00

abstract：:A novel glycosaminoglycan-like sulfated polysaccharide (AAP) from the pleopods of Haliotis discus hannai Ino was purified by DEAE ion exchange chromatography followed with S-300 HR geltrion chromatography. Chemical composition analysis indicated that AAP was composed of galactosamine, glucuronic acid, fucose, galactos...

journal_title：International journal of biological macromolecules

authors： Li G,Chen S,Wang Y,Xue Y,Chang Y,Li Z,Wang J,Xue C

更新日期：2011-12-01 00:00:00

abstract：:An algal extracellular biopolymer (over 8.5 × 10(5)Da) composed of carbohydrates (52%) and protein (∼13%) has been isolated from a red alga Rhodella grisea growing in natural conditions by concentration of water medium, alcohol precipitation, dialysis and freeze-drying. This mucilagineous biopolymer contained xylose a...

journal_title：International journal of biological macromolecules

authors： Nosáľová G,Capek P,Flešková D,Jureček L,Hindák F,Lukavský J,Cepák V,Ray B,Breierová E,Turjan J

更新日期：2011-12-01 00:00:00

abstract：:Alginate (ALg)-human-like collagen (HLC) microspheres were prepared by the technology of electrostatic droplet generation in order to develop a biocompatible vehicle for probiotic bacteria. Microparticles were spherical with mean particle size of 400μm. The encapsulation efficiency (EE) of ALg-HLC microspheres could r...

journal_title：International journal of biological macromolecules

authors： Su R,Zhu XL,Fan DD,Mi Y,Yang CY,Jia X

更新日期：2011-12-01 00:00:00

abstract：:An acetylcholinesterase (AChE) purified from rat brain was immobilized onto gold nanoparticles (AuNPs) assembled on the surface of porous calcium carbonate (CaCO(3)) microsphere. The resulting AChE-AuNPs-CaCO(3) bioconjugate was mounted on the surface of Au electrode with the help of silica sol-gel matrix to prepare t...

journal_title：International journal of biological macromolecules

authors： Chauhan N,Narang J,Pundir CS

更新日期：2011-12-01 00:00:00

abstract：:It has been established that the equilibrium between duplex and G-quadruplex of the nuclease hypersensitivity element III1 (NHE III1) in human c-myc promoter is linked with this gene's transcription. Using NMR and ESI-MS, we have found a pyrene derivative, DMAPP, is able to modulate this equilibrium and, thus, might h...

journal_title：International journal of biological macromolecules

authors： Zhang Z,He X,Yuan G

更新日期：2011-12-01 00:00:00